Posted on 22 Feb 2026

Senior Principal R&D Engineer - Cardiac Ablation (PFA/RFA)

Irvine, CA (Hybrid/Onsite)
Permanent
$140,000 - $200,000

Overview

ACE Partners is supporting a venture-backed medical device startup developing next-generation transcatheter ablation technologies for cardiovascular applications.

The company is seeking a Senior Principal R&D Engineer with deep expertise in PFA and/or RFA ablation systems to lead technical innovation across catheter design, energy delivery, and system performance. The role offers flexibility in structure (FTE, part-time, or consulting) depending on experience and availability.

The Role

You will play a key technical leadership role in the design and development of catheter-based ablation systems, working closely with clinical partners and internal stakeholders to translate procedural needs into robust, manufacturable solutions.

Key Responsibilities 

  • Lead concept generation, design, prototyping, and bench testing of PFA/RFA ablation catheters
  • Drive optimisation of electrode design, materials, and catheter mechanics
  • Provide technical leadership on electrical and energy delivery systems, including waveform development and insulation strategies
  • Partner with electrophysiologists and interventional cardiologists to inform design decisions
  • Contribute to intellectual property, invention disclosures, and patent development
  • Support system-level verification and validation, including electrical safety and performance testing

Background & Experience

  • Advanced degree in Electrical Engineering, Biomedical Engineering, or related discipline
  • Extensive hands-on experience developing PFA and/or RFA catheter systems
  • Strong understanding of cardiac anatomy, electrophysiology, and clinical workflows
  • Familiarity with imaging modalities used in catheter-based procedures
  • Comfortable operating independently in a fast-paced startup environment

Why You Should Apply

  • Lead cutting-edge PFA/RFA technology at an early and influential stage
  • High-impact role with real technical ownership and clinical visibility
  • Flexible engagement model (full-time, part-time, or consulting)
  • Opportunity to shape next-generation cardiovascular therapies alongside experienced clinicians and engineers
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